Learn more about this rare disease, how it affects our families, and how we're helping to find treatment.
Resources
Thanks to participation from various physicians, researchers, and SHINE Syndrome Families, we have been able to build a library of helpful and informational videos detailing DLG4 Synaptopathy, it’s effects, current research, and the impact of getting involved in the community. This page includes some of the more popular videos published so far as well as access to additional content for those interested. If you’re new to the community, these are a great place to start gathering information!
DLG4 SHINE Documentary
In 2022, SHINE Syndrome Foundation was able to secure a grant for the purpose of developing a documentary film about SHINE Syndrome. After several months of planning, filming, and editing, the final video is here and available for all. Please take the time to watch and learn a little about families living with SHINE Syndrome, characteristics of the disease, and fundraising and research initiatives in progress to help those affected.
All About DLG4 SHINE Webinar Series
MAB member Alexandre White-Brown has developed this series of videos to describe some common facts about DLG4 and PSD95. These informational videos can also be found on our DLG4 SHINE YouTube Channel.
All About DLG4 SHINE Episode 1 - DLG4 Basics
In this video, Alexandre White-Brown starts off our informational series on DLG4 Synaptopathy, or SHINE Syndrome, by describing the basic functions and purpose of the DLG4 gene.
All About DLG4 SHINE Episode 2 - PSD95 Function
For the second video in his series, Alexandre White-Brown discusses how DNA is read by RNA to create the PSD95 protein and the functions of that protein in the brain.
All About DLG4 SHINE Episode 3 - Variant Types
In his third installment, Alexandre White-Brown discusses the different types of genetic variants and the resulting change to gene functionality and PSD-95 protein production.